Polysorbate 20

1. Product Identification
Synonyms: Polyoxyethylene sorbitan monolaurate; Polysorbate 20 NF
CAS No.: 9005-64-5
Molecular Weight: Not applicable to mixtures.
Chemical Formula: Not applicable to mixtures.
Product Codes:

2. Composition/Information on Ingredients


Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------

Polysorbate 20 9005-64-5 100% Yes

3. Hazards Identification
Emergency Overview
--------------------------
CAUTION! MAY CAUSE IRRITATION TO SKIN AND EYES.

SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------

Health Rating: 1 - Slight
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Green (General Storage)
-----------------------------------------------------------------------------------------------------------


Potential Health Effects
----------------------------------

Inhalation:
Not expected to be a health hazard.
Ingestion:
Large doses may produce abdominal spasms, diarrhea.
Skin Contact:
May cause irritation or sensitization in sensitive individuals.
Eye Contact:
May cause irritation.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.

4. First Aid Measures
Inhalation:
Not expected to require first aid measures. Remove to fresh air. Get medical
attention for any breathing difficulty.
Ingestion:
Give several glasses of water to drink to dilute. If large amounts were
swallowed, get medical advice.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes.
Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting
upper and lower eyelids occasionally. Get medical attention if irritation
persists.


5. Fire Fighting Measures
Fire:
Flash point: 148C (298F) CC
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full face piece operated in the
pressure demand or other positive pressure mode.

6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective
equipment as specified in Section 8. Contain and recover liquid when possible.
Collect liquid in an appropriate container or absorb with an inert material
(e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer!

7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Containers of this material may be hazardous
when empty since they retain product residues (vapors, liquid); observe all
warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
Not expected to require any special ventilation.
Personal Respirators (NIOSH Approved):
Not expected to require personal respirator usage.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties
Appearance:
Amber liquid.
Odor:
No information found.
Solubility:
Soluble in water.
Specific Gravity:
1.11
pH:
No information found.
% Volatiles by volume @ 21C (70F):
3.0
Boiling Point:
> 100C (> 212F)
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
< 1.0 @ 20C (68F)
Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers, acids.
Conditions to Avoid:
Incompatibles.

11. Toxicological Information

Oral rat LD50: 36,700mg/kg. Investigated as a reproductive effector.

--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Polysorbate 20 (9005-64-5) No No None


12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.

13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options. State
and local disposal regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state and
local requirements.

14. Transport Information
Not regulated.


15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Polysorbate 20 (9005-64-5) Yes No Yes Yes

--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Polysorbate 20 (9005-64-5) Yes Yes No Yes

--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Polysorbate 20 (9005-64-5) No No No No

--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Polysorbate 20 (9005-64-5) No No No


Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Liquid)

Australian Hazchem Code: None allocated.
Poison Schedule: None allocated
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled
Products Regulations (CPR) and the MSDS contains all of the information
required by the CPR.


16. Other Information
NFPA Ratings: Health: 1 Flammability: 0 Reactivity: 0
Label Hazard Warning:
CAUTION! MAY CAUSE IRRITATION TO SKIN AND EYES.
Label Precautions:
Avoid contact with eyes, skin and clothing.
Keep container closed.
Wash thoroughly after handling.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at
least 15 minutes. Get medical attention if irritation develops or persists.
Product Use:
Laboratory Reagent. NOT INTENDED FOR INJECTABLE DRUG USE.


Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)